Identification of Key Receptor Residues Discriminating Human Chorionic Gonadotropin (hCG)- and Luteinizing Hormone (LH)-Specific Signaling

(1) The human luteinizing hormone (LH)/chorionic gonadotropin (hCG) receptor (LHCGR) discriminates its two hormone ligands and differs from the murine receptor (Lhr) in amino acid residues potentially involved in qualitative discerning of LH and hCG. The latter gonadotropin is absent in rodents. The...

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Detalles Bibliográficos
Autores principales: Lazzaretti, Clara, Secco, Valentina, Paradiso, Elia, Sperduti, Samantha, Rutz, Claudia, Kreuchwig, Annika, Krause, Gerd, Simoni, Manuela, Casarini, Livio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794846/
https://www.ncbi.nlm.nih.gov/pubmed/33375708
http://dx.doi.org/10.3390/ijms22010151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794846/
https://www.ncbi.nlm.nih.gov/pubmed/33375708
http://dx.doi.org/10.3390/ijms22010151

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