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Drug Conjugates Based on a Monovalent Affibody Targeting Vector Can Efficiently Eradicate HER2 Positive Human Tumors in an Experimental Mouse Model

SIMPLE SUMMARY: Drug conjugates, consisting of a tumor targeting part coupled to a highly toxic molecule, are promising for treatment of many different types of cancer. However, for many patients it is not curative, and investigation of alternative or complimentary types of drug conjugates is motiva...

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Detalles Bibliográficos
Autores principales: Xu, Tianqi, Ding, Haozhong, Vorobyeva, Anzhelika, Oroujeni, Maryam, Orlova, Anna, Tolmachev, Vladimir, Gräslund, Torbjörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794879/
https://www.ncbi.nlm.nih.gov/pubmed/33396753
http://dx.doi.org/10.3390/cancers13010085