The Bromodomain Inhibitor, INCB057643, Targets Both Cancer Cells and the Tumor Microenvironment in Two Preclinical Models of Pancreatic Cancer

SIMPLE SUMMARY: Pancreatic cancer remains a highly lethal disease, with only ~10% of patients still alive five years after diagnosis, as most patients already have advanced, metastatic disease at the time of diagnosis. Therefore, new treatments are needed for these patients. We tested INCB057643, a...

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Detalles Bibliográficos
Autores principales: Leal, Ana S., Liu, Phillip, Krieger-Burke, Teresa, Ruggeri, Bruce, Liby, Karen T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794921/
https://www.ncbi.nlm.nih.gov/pubmed/33396954
http://dx.doi.org/10.3390/cancers13010096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794921/
https://www.ncbi.nlm.nih.gov/pubmed/33396954
http://dx.doi.org/10.3390/cancers13010096

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