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The Bromodomain Inhibitor, INCB057643, Targets Both Cancer Cells and the Tumor Microenvironment in Two Preclinical Models of Pancreatic Cancer
SIMPLE SUMMARY: Pancreatic cancer remains a highly lethal disease, with only ~10% of patients still alive five years after diagnosis, as most patients already have advanced, metastatic disease at the time of diagnosis. Therefore, new treatments are needed for these patients. We tested INCB057643, a...
Autores principales: | Leal, Ana S., Liu, Phillip, Krieger-Burke, Teresa, Ruggeri, Bruce, Liby, Karen T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794921/ https://www.ncbi.nlm.nih.gov/pubmed/33396954 http://dx.doi.org/10.3390/cancers13010096 |
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