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The Influence of Chimeric Antigen Receptor Structural Domains on Clinical Outcomes and Associated Toxicities
SIMPLE SUMMARY: The development and refinement chimeric antigen receptor (CAR)-T cell immunotherapy has significantly improved the prognosis of patients with B cell malignancies. Severe treatment related toxicities however remain a significant challenge for the field. This perspective reviews 17 cli...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794933/ https://www.ncbi.nlm.nih.gov/pubmed/33375550 http://dx.doi.org/10.3390/cancers13010038 |