The Influence of Chimeric Antigen Receptor Structural Domains on Clinical Outcomes and Associated Toxicities

SIMPLE SUMMARY: The development and refinement chimeric antigen receptor (CAR)-T cell immunotherapy has significantly improved the prognosis of patients with B cell malignancies. Severe treatment related toxicities however remain a significant challenge for the field. This perspective reviews 17 cli...

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Detalles Bibliográficos
Autores principales: Davey, Ashleigh S., Call, Matthew E., Call, Melissa J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794933/
https://www.ncbi.nlm.nih.gov/pubmed/33375550
http://dx.doi.org/10.3390/cancers13010038

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