Alterations in the Genomic Distribution of 5hmC in In Vivo Aged Human Skin Fibroblasts

5-Hydroxymethylcytosine (5hmC) is a functionally active epigenetic modification. We analyzed whether changes in DNA 5-hydroxymethylation are an element of age-related epigenetic drift. We tested primary fibroblast cultures originating from individuals aged 22–35 years and 74–94 years. Global quantit...

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Detalles Bibliográficos
Autores principales: Kołodziej-Wojnar, Paulina, Borkowska, Joanna, Wicik, Zofia, Domaszewska-Szostek, Anna, Połosak, Jacek, Cąkała-Jakimowicz, Marta, Bujanowska, Olga, Puzianowska-Kuznicka, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794952/
https://www.ncbi.nlm.nih.gov/pubmed/33374812
http://dx.doi.org/10.3390/ijms22010078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794952/
https://www.ncbi.nlm.nih.gov/pubmed/33374812
http://dx.doi.org/10.3390/ijms22010078

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