ATM Kinase Inhibition Preferentially Sensitises PTEN-Deficient Prostate Tumour Cells to Ionising Radiation

SIMPLE SUMMARY: Prostate cancer is the most frequently diagnosed cancer in men. Despite the importance of radical radiotherapy for the management of this disease, recurrence remains a challenge. PTEN is a tumour suppressor that is frequently inactivated in advanced prostate cancer and has been assoc...

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Detalles Bibliográficos
Autores principales: Hanna, Conor, Dunne, Victoria L., Walker, Steven M., Butterworth, Karl T., McCabe, Nuala, Waugh, David J. J., Kennedy, Richard D., Prise, Kevin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794981/
https://www.ncbi.nlm.nih.gov/pubmed/33396656
http://dx.doi.org/10.3390/cancers13010079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794981/
https://www.ncbi.nlm.nih.gov/pubmed/33396656
http://dx.doi.org/10.3390/cancers13010079

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