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ATM Kinase Inhibition Preferentially Sensitises PTEN-Deficient Prostate Tumour Cells to Ionising Radiation
SIMPLE SUMMARY: Prostate cancer is the most frequently diagnosed cancer in men. Despite the importance of radical radiotherapy for the management of this disease, recurrence remains a challenge. PTEN is a tumour suppressor that is frequently inactivated in advanced prostate cancer and has been assoc...
Autores principales: | Hanna, Conor, Dunne, Victoria L., Walker, Steven M., Butterworth, Karl T., McCabe, Nuala, Waugh, David J. J., Kennedy, Richard D., Prise, Kevin M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794981/ https://www.ncbi.nlm.nih.gov/pubmed/33396656 http://dx.doi.org/10.3390/cancers13010079 |
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