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Hybrid E/M Phenotype(s) and Stemness: A Mechanistic Connection Embedded in Network Topology
Metastasis remains an unsolved clinical challenge. Two crucial features of metastasizing cancer cells are (a) their ability to dynamically move along the epithelial–hybrid–mesenchymal spectrum and (b) their tumor initiation potential or stemness. With increasing functional characterization of hybrid...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794989/ https://www.ncbi.nlm.nih.gov/pubmed/33375334 http://dx.doi.org/10.3390/jcm10010060 |