Cargando…

Hybrid E/M Phenotype(s) and Stemness: A Mechanistic Connection Embedded in Network Topology

Metastasis remains an unsolved clinical challenge. Two crucial features of metastasizing cancer cells are (a) their ability to dynamically move along the epithelial–hybrid–mesenchymal spectrum and (b) their tumor initiation potential or stemness. With increasing functional characterization of hybrid...

Descripción completa

Detalles Bibliográficos
Autores principales: Pasani, Satwik, Sahoo, Sarthak, Jolly, Mohit Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794989/
https://www.ncbi.nlm.nih.gov/pubmed/33375334
http://dx.doi.org/10.3390/jcm10010060