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Dynamical Correlations Reveal Allosteric Sites in G Protein-Coupled Receptors

G protein-coupled Receptors (GPCRs) play a central role in many physiological processes and, consequently, constitute important drug targets. In particular, the search for allosteric drugs has recently drawn attention, since they could be more selective and lead to fewer side effects. Accordingly, c...

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Detalles Bibliográficos
Autores principales: Renault, Pedro, Giraldo, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795036/
https://www.ncbi.nlm.nih.gov/pubmed/33375427
http://dx.doi.org/10.3390/ijms22010187