In Silico and In Vitro Analysis of Major Cannabis-Derived Compounds as Fatty Acid Amide Hydrolase Inhibitors

Accumulated evidence suggests that enhancing the endocannabinoid (eCB) tone, in particular of anandamide (N-arachidonoylethanolamine, AEA), has therapeutic potential in many human diseases. Fatty acid amide hydrolase (FAAH) is a membrane-bound enzyme principally responsible for the degradation of AE...

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Detalles Bibliográficos
Autores principales: Criscuolo, Emanuele, De Sciscio, Maria Laura, Fezza, Filomena, Maccarrone, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795171/
https://www.ncbi.nlm.nih.gov/pubmed/33374180
http://dx.doi.org/10.3390/molecules26010048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795171/
https://www.ncbi.nlm.nih.gov/pubmed/33374180
http://dx.doi.org/10.3390/molecules26010048

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