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In Silico and In Vitro Analysis of Major Cannabis-Derived Compounds as Fatty Acid Amide Hydrolase Inhibitors
Accumulated evidence suggests that enhancing the endocannabinoid (eCB) tone, in particular of anandamide (N-arachidonoylethanolamine, AEA), has therapeutic potential in many human diseases. Fatty acid amide hydrolase (FAAH) is a membrane-bound enzyme principally responsible for the degradation of AE...
Autores principales: | Criscuolo, Emanuele, De Sciscio, Maria Laura, Fezza, Filomena, Maccarrone, Mauro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795171/ https://www.ncbi.nlm.nih.gov/pubmed/33374180 http://dx.doi.org/10.3390/molecules26010048 |
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