Preparation and Solid-State Characterization of Eltrombopag Crystal Phases

Eltrombopag, of C(25)H(22)N(4)O(4) chemical formula, is a drug used against thrombocytopenia, marketed worldwide under different tradenames in the form of its bis-olamine salt. The free acid (CAS no. 496775-61-2) is an intermediate species used for the final drug isolation and is reported to crystal...

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Detalles Bibliográficos
Autores principales: Abbinante, Vincenzo Mirco, Zampieri, Massimo, Barreca, Giuseppe, Masciocchi, Norberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795200/
https://www.ncbi.nlm.nih.gov/pubmed/33375645
http://dx.doi.org/10.3390/molecules26010065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795200/
https://www.ncbi.nlm.nih.gov/pubmed/33375645
http://dx.doi.org/10.3390/molecules26010065

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