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Systems Approach to Pathogenic Mechanism of Type 2 Diabetes and Drug Discovery Design Based on Deep Learning and Drug Design Specifications

In this study, we proposed a systems biology approach to investigate the pathogenic mechanism for identifying significant biomarkers as drug targets and a systematic drug discovery strategy to design a potential multiple-molecule targeting drug for type 2 diabetes (T2D) treatment. We first integrate...

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Detalles Bibliográficos
Autores principales: Chang, Shen, Chen, Jian-You, Chuang, Yung-Jen, Chen, Bor-Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795239/
https://www.ncbi.nlm.nih.gov/pubmed/33375269
http://dx.doi.org/10.3390/ijms22010166