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Systems Approach to Pathogenic Mechanism of Type 2 Diabetes and Drug Discovery Design Based on Deep Learning and Drug Design Specifications
In this study, we proposed a systems biology approach to investigate the pathogenic mechanism for identifying significant biomarkers as drug targets and a systematic drug discovery strategy to design a potential multiple-molecule targeting drug for type 2 diabetes (T2D) treatment. We first integrate...
Autores principales: | Chang, Shen, Chen, Jian-You, Chuang, Yung-Jen, Chen, Bor-Sen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795239/ https://www.ncbi.nlm.nih.gov/pubmed/33375269 http://dx.doi.org/10.3390/ijms22010166 |
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