Intra-Cellular Calcium Signaling Pathways (PKC, RAS/RAF/MAPK, PI3K) in Lamina Cribrosa Cells in Glaucoma

The lamina cribrosa (LC) is a key site of fibrotic damage in glaucomatous optic neuropathy and the precise mechanisms of LC change remain unclear. Elevated Ca(2+) is a major driver of fibrosis, and therefore intracellular Ca(2+) signaling pathways are relevant glaucoma-related mechanisms that need t...

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Detalles Bibliográficos
Autores principales: Irnaten, Mustapha, Duff, Aisling, Clark, Abbot, O’Brien, Colm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795259/
https://www.ncbi.nlm.nih.gov/pubmed/33375386
http://dx.doi.org/10.3390/jcm10010062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795259/
https://www.ncbi.nlm.nih.gov/pubmed/33375386
http://dx.doi.org/10.3390/jcm10010062

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