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Identification of Immunological Parameters as Predictive Biomarkers of Relapse in Patients with Chronic Myeloid Leukemia on Treatment-Free Remission

BCR-ABL is an aberrant tyrosine kinase responsible for chronic myeloid leukemia (CML). Tyrosine kinase inhibitors (TKIs) induce a potent antileukemic response mostly based on the inhibition of BCR-ABL, but they also increase the activity of Natural Killer (NK) and CD8+ T cells. After several years,...

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Detalles Bibliográficos
Autores principales: Vigón, Lorena, Luna, Alejandro, Galán, Miguel, Rodríguez-Mora, Sara, Fuertes, Daniel, Mateos, Elena, Piris-Villaespesa, Miguel, Bautista, Guiomar, San José, Esther, Rivera-Torres, José, Steegmann, Juan Luis, de Ory, Fernando, Pérez-Olmeda, Mayte, Alcamí, José, Planelles, Vicente, López-Huertas, María Rosa, García-Gutiérrez, Valentín, Coiras, Mayte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795332/
https://www.ncbi.nlm.nih.gov/pubmed/33375572
http://dx.doi.org/10.3390/jcm10010042