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Metabolic Reprogramming of Fibroblasts as Therapeutic Target in Rheumatoid Arthritis and Cancer: Deciphering Key Mechanisms Using Computational Systems Biology Approaches

SIMPLE SUMMARY: Fibroblasts are critical regulators of several physiological processes linked to extracellular matrix regulation. Under certain conditions, fibroblasts can also transform into more aggressive phenotypes and contribute to disease pathophysiology. In this review, we highlight metabolic...

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Detalles Bibliográficos
Autores principales: Aghakhani, Sahar, Zerrouk, Naouel, Niarakis, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795338/
https://www.ncbi.nlm.nih.gov/pubmed/33374292
http://dx.doi.org/10.3390/cancers13010035