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Metabolic Reprogramming of Fibroblasts as Therapeutic Target in Rheumatoid Arthritis and Cancer: Deciphering Key Mechanisms Using Computational Systems Biology Approaches
SIMPLE SUMMARY: Fibroblasts are critical regulators of several physiological processes linked to extracellular matrix regulation. Under certain conditions, fibroblasts can also transform into more aggressive phenotypes and contribute to disease pathophysiology. In this review, we highlight metabolic...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795338/ https://www.ncbi.nlm.nih.gov/pubmed/33374292 http://dx.doi.org/10.3390/cancers13010035 |