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Coenzyme Q Depletion Reshapes MCF-7 Cells Metabolism

Mitochondrial dysfunction plays a significant role in the metabolic flexibility of cancer cells. This study aimed to investigate the metabolic alterations due to Coenzyme Q depletion in MCF-7 cells. Method: The Coenzyme Q depletion was induced by competitively inhibiting with 4-nitrobenzoate the coq...

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Detalles Bibliográficos
Autores principales: Wang, Wenping, Liparulo, Irene, Rizzardi, Nicola, Bolignano, Paola, Calonghi, Natalia, Bergamini, Christian, Fato, Romana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795339/
https://www.ncbi.nlm.nih.gov/pubmed/33379147
http://dx.doi.org/10.3390/ijms22010198