Disruption of Abcc6 Transporter in Zebrafish Causes Ocular Calcification and Cardiac Fibrosis

Pseudoxanthoma elasticum (PXE), caused by ABCC6/MRP6 mutation, is a heritable multisystem disorder in humans. The progressive clinical manifestations of PXE are accompanied by ectopic mineralization in various connective tissues. However, the pathomechanisms underlying the PXE multisystem disorder r...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Jianjian, She, Peilu, Liu, Xu, Gao, Bangjun, Jin, Daqin, Zhong, Tao P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795442/
https://www.ncbi.nlm.nih.gov/pubmed/33383974
http://dx.doi.org/10.3390/ijms22010278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795442/
https://www.ncbi.nlm.nih.gov/pubmed/33383974
http://dx.doi.org/10.3390/ijms22010278

Ejemplares similares