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Disruption of Abcc6 Transporter in Zebrafish Causes Ocular Calcification and Cardiac Fibrosis

Pseudoxanthoma elasticum (PXE), caused by ABCC6/MRP6 mutation, is a heritable multisystem disorder in humans. The progressive clinical manifestations of PXE are accompanied by ectopic mineralization in various connective tissues. However, the pathomechanisms underlying the PXE multisystem disorder r...

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Detalles Bibliográficos
Autores principales:	Sun, Jianjian, She, Peilu, Liu, Xu, Gao, Bangjun, Jin, Daqin, Zhong, Tao P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795442/ https://www.ncbi.nlm.nih.gov/pubmed/33383974 http://dx.doi.org/10.3390/ijms22010278

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