N-phenyl-6-chloro-4-hydroxy-2-quinolone-3-carboxamides: Molecular Docking, Synthesis, and Biological Investigation as Anticancer Agents

Cancer is a multifactorial disease and the second leading cause of death worldwide. Diverse factors induce carcinogenesis, such as diet, smoking, radiation, and genetic defects. The phosphatidylinositol 3-kinase (PI3Kα) has emerged as an attractive target for anticancer drug design. Eighteen derivat...

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Detalles Bibliográficos
Autores principales: Sabbah, Dima A., Haroon, Rawan A., Bardaweel, Sanaa K., Hajjo, Rima, Sweidan, Kamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795513/
https://www.ncbi.nlm.nih.gov/pubmed/33375766
http://dx.doi.org/10.3390/molecules26010073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795513/
https://www.ncbi.nlm.nih.gov/pubmed/33375766
http://dx.doi.org/10.3390/molecules26010073

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