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Exosomal miRNAs as Potential Biomarkers to Monitor Phosphodiesterase 5 Inhibitor Induced Anti-Fibrotic Effects on CCl(4) Treated Rats

MicroRNAs (miRNAs) are short, non-coding RNA species that are important post-transcriptional regulators of gene expression and play an important role in the pathogenesis of non-alcoholic fatty liver disease. Here, we investigated the phosphodiesterase 5 (PDE5) inhibitor induced effects on hepatic an...

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Detalles Bibliográficos
Autores principales: Broermann, Andre, Schmid, Ramona, Gabrielyan, Ogsen, Sakowski, Marlene, Eisele, Claudia, Keller, Sascha, Wolff, Michael, Baum, Patrick, Stierstorfer, Birgit, Huber, Jochen, Krämer, Bernhard K., Hocher, Berthold, Streicher, Ruediger, Delić, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795540/
https://www.ncbi.nlm.nih.gov/pubmed/33396535
http://dx.doi.org/10.3390/ijms22010382