The Next-Generation Immune Checkpoint LAG-3 and Its Therapeutic Potential in Oncology: Third Time’s a Charm

The blockade of immune checkpoints (ICPs), such as cytotoxic T lymphocyte associated protein-4 (CTLA-4) and programmed death-1 (PD-1) and its ligand (PD-L1), has propelled the field of immuno-oncology into its current era. Drugs targeting these ICPs have improved clinical outcome in a number of pati...

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Detalles Bibliográficos
Autores principales: Lecocq, Quentin, Keyaerts, Marleen, Devoogdt, Nick, Breckpot, Karine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795594/
https://www.ncbi.nlm.nih.gov/pubmed/33374804
http://dx.doi.org/10.3390/ijms22010075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795594/
https://www.ncbi.nlm.nih.gov/pubmed/33374804
http://dx.doi.org/10.3390/ijms22010075

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