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Endoglin Targeting: Lessons Learned and Questions That Remain

Approximately 30 years ago, endoglin was identified as a transforming growth factor (TGF)-β coreceptor with a crucial role in developmental biology and tumor angiogenesis. Its selectively high expression on tumor vessels and its correlation with poor survival in cancer patients led to the exploratio...

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Detalles Bibliográficos
Autores principales: Liu, Yingmiao, Paauwe, Madelon, Nixon, Andrew B., Hawinkels, Lukas J.A.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795616/
https://www.ncbi.nlm.nih.gov/pubmed/33375670
http://dx.doi.org/10.3390/ijms22010147