Synthesis and Biological Evaluation of Bicalutamide Analogues for the Potential Treatment of Prostate Cancer

The androgen receptor (AR) is a pivotal target for the treatment of prostate cancer (PC) even when the disease progresses toward androgen-independent or castration-resistant forms. In this study, a series of 15 bicalutamide analogues (sulfide, deshydroxy, sulfone, and O-acetylated) were prepared and...

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Detalles Bibliográficos
Autores principales: Kandil, Sahar B., McGuigan, Christopher, Westwell, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795644/
https://www.ncbi.nlm.nih.gov/pubmed/33374450
http://dx.doi.org/10.3390/molecules26010056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795644/
https://www.ncbi.nlm.nih.gov/pubmed/33374450
http://dx.doi.org/10.3390/molecules26010056

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