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Specific Targeting of PEGylated Liposomal Doxorubicin (Doxil(®)) to Tumour Cells Using a Novel TIMP3 Peptide

Doxorubicin is a cytotoxic anthracycline derivative that has been used as a chemotherapeutic in many different forms of human cancer with some success. However, doxorubicin treatment has several side-effects, the most serious of which is cardiomyopathy, that can be fatal. Doxorubicin encapsulation i...

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Detalles Bibliográficos
Autores principales: Aldughaim, Mohammed S., Muthana, Munitta, Alsaffar, Fatimah, Barker, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795762/
https://www.ncbi.nlm.nih.gov/pubmed/33379361
http://dx.doi.org/10.3390/molecules26010100