KRAS Promoter G-Quadruplexes from Sequences of Different Length: A Physicochemical Study

DNA G-quadruplexes (G4s) form in relevant genomic regions and intervene in several biological processes, including the modulation of oncogenes expression, and are potential anticancer drug targets. The human KRAS proto-oncogene promoter region contains guanine-rich sequences able to fold into G4 str...

Descripción completa

Detalles Bibliográficos
Autores principales: D’Aria, Federica, Pagano, Bruno, Petraccone, Luigi, Giancola, Concetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795837/
https://www.ncbi.nlm.nih.gov/pubmed/33466280
http://dx.doi.org/10.3390/ijms22010448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795837/
https://www.ncbi.nlm.nih.gov/pubmed/33466280
http://dx.doi.org/10.3390/ijms22010448

Ejemplares similares