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KRAS Promoter G-Quadruplexes from Sequences of Different Length: A Physicochemical Study
DNA G-quadruplexes (G4s) form in relevant genomic regions and intervene in several biological processes, including the modulation of oncogenes expression, and are potential anticancer drug targets. The human KRAS proto-oncogene promoter region contains guanine-rich sequences able to fold into G4 str...
Autores principales: | D’Aria, Federica, Pagano, Bruno, Petraccone, Luigi, Giancola, Concetta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795837/ https://www.ncbi.nlm.nih.gov/pubmed/33466280 http://dx.doi.org/10.3390/ijms22010448 |
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