NPM-ALK: A Driver of Lymphoma Pathogenesis and a Therapeutic Target

SIMPLE SUMMARY: Anaplastic lymphoma kinase (ALK) is a tyrosine kinase associated with Anaplastic Large Cell lymphoma (ALCL) through oncogenic translocations mainly NPM-ALK. Chemotherapy is effective in ALK(+) ALCL patients and induces remission rates of approximately 80%. The remaining patients do n...

Descripción completa

Detalles Bibliográficos
Autores principales: Andraos, Elissa, Dignac, Joséphine, Meggetto, Fabienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795840/
https://www.ncbi.nlm.nih.gov/pubmed/33466277
http://dx.doi.org/10.3390/cancers13010144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795840/
https://www.ncbi.nlm.nih.gov/pubmed/33466277
http://dx.doi.org/10.3390/cancers13010144

Ejemplares similares