Cathepsin B Localizes in the Caveolae and Participates in the Proteolytic Cascade in Trabecular Meshwork Cells. Potential New Drug Target for the Treatment of Glaucoma

Extracellular matrix (ECM) deposition in the trabecular meshwork (TM) is one of the hallmarks of glaucoma, a group of human diseases and leading cause of permanent blindness. The molecular mechanisms underlying ECM deposition in the glaucomatous TM are not known, but it is presumed to be a consequen...

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Detalles Bibliográficos
Autores principales: Nettesheim, April, Shim, Myoung Sup, Dixon, Angela, Raychaudhuri, Urmimala, Gong, Haiyan, Liton, Paloma B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795952/
https://www.ncbi.nlm.nih.gov/pubmed/33379277
http://dx.doi.org/10.3390/jcm10010078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795952/
https://www.ncbi.nlm.nih.gov/pubmed/33379277
http://dx.doi.org/10.3390/jcm10010078

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