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Studies of Coumarin Derivatives for Constitutive Androstane Receptor (CAR) Activation

Constitutive androstane receptor (CAR) activation has found to ameliorate diabetes in animal models. However, no CAR agonists are available clinically. Therefore, a safe and effective CAR activator would be an alternative option. In this study, sixty courmarin derivatives either synthesized or purif...

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Detalles Bibliográficos
Autores principales: Juang, Shin-Hun, Hsieh, Min-Tsang, Hsu, Pei-Ling, Chen, Ju-Ling, Liu, Hui-Kang, Liang, Fong-Pin, Kuo, Sheng-Chu, Chiu, Chen-Yuan, Liu, Shing-Hwa, Chou, Chen-Hsi, Wu, Tian-Shung, Hung, Hsin-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796031/
https://www.ncbi.nlm.nih.gov/pubmed/33396516
http://dx.doi.org/10.3390/molecules26010164