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The Influence of Temperature and Viscosity of Polyethylene Glycol on the Rate of Microwave-Induced In Situ Amorphization of Celecoxib

Microwaved-induced in situ amorphization of a drug in a polymer has been suggested to follow a dissolution process, with the drug dissolving into the mobile polymer at temperatures above the glass transition temperature (T(g)) of the polymer. Thus, based on the Noyes–Whitney and the Stoke–Einstein e...

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Detalles Bibliográficos
Autores principales: Hempel, Nele-Johanna, Dao, Tra, Knopp, Matthias M., Berthelsen, Ragna, Löbmann, Korbinian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796040/
https://www.ncbi.nlm.nih.gov/pubmed/33383672
http://dx.doi.org/10.3390/molecules26010110