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Denosumab Discontinuation and the Rebound Phenomenon: A Narrative Review

Denosumab is a potent antiresorptive agent that substantially increases bone mineral density and reduces fracture rates at all skeletal sites for as long as it is administered. However, its favorable skeletal effects reverse quickly upon its discontinuation, because of a vast increase of osteoclast...

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Detalles Bibliográficos
Autores principales: Anastasilakis, Athanasios D., Makras, Polyzois, Yavropoulou, Maria P., Tabacco, Gaia, Naciu, Anda Mihaela, Palermo, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796169/
https://www.ncbi.nlm.nih.gov/pubmed/33406802
http://dx.doi.org/10.3390/jcm10010152