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Denosumab Discontinuation and the Rebound Phenomenon: A Narrative Review
Denosumab is a potent antiresorptive agent that substantially increases bone mineral density and reduces fracture rates at all skeletal sites for as long as it is administered. However, its favorable skeletal effects reverse quickly upon its discontinuation, because of a vast increase of osteoclast...
Autores principales: | Anastasilakis, Athanasios D., Makras, Polyzois, Yavropoulou, Maria P., Tabacco, Gaia, Naciu, Anda Mihaela, Palermo, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796169/ https://www.ncbi.nlm.nih.gov/pubmed/33406802 http://dx.doi.org/10.3390/jcm10010152 |
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