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Role of PUM RNA-Binding Proteins in Cancer

SIMPLE SUMMARY: PUM1 and PUM2 are RNA-binding Pumilio proteins controlling the accessibility of hundreds of mRNAs for translation in a variety of human tissues. As a result, PUMs exemplify one of the mechanisms safeguarding the cellular proteome. PUM expression is disturbed in cancer, resulting in d...

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Detalles Bibliográficos
Autores principales: Smialek, Maciej J., Ilaslan, Erkut, Sajek, Marcin P., Jaruzelska, Jadwiga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796173/
https://www.ncbi.nlm.nih.gov/pubmed/33401540
http://dx.doi.org/10.3390/cancers13010129