Cargando…
Role of PUM RNA-Binding Proteins in Cancer
SIMPLE SUMMARY: PUM1 and PUM2 are RNA-binding Pumilio proteins controlling the accessibility of hundreds of mRNAs for translation in a variety of human tissues. As a result, PUMs exemplify one of the mechanisms safeguarding the cellular proteome. PUM expression is disturbed in cancer, resulting in d...
Autores principales: | Smialek, Maciej J., Ilaslan, Erkut, Sajek, Marcin P., Jaruzelska, Jadwiga |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796173/ https://www.ncbi.nlm.nih.gov/pubmed/33401540 http://dx.doi.org/10.3390/cancers13010129 |
Ejemplares similares
-
Characterization of RNP Networks of PUM1 and PUM2 Post-Transcriptional Regulators in TCam-2 Cells, a Human Male Germ Cell Model
por: Smialek, Maciej J., et al.
Publicado: (2020) -
Emerging Roles of NANOS RNA-Binding Proteins in Cancer
por: Ilaslan, Erkut, et al.
Publicado: (2022) -
Distinct Roles of NANOS1 and NANOS3 in the Cell Cycle and NANOS3-PUM1-FOXM1 Axis to Control G2/M Phase in a Human Primordial Germ Cell Model
por: Ilaslan, Erkut, et al.
Publicado: (2022) -
Human NANOS1 Represses Apoptosis by Downregulating Pro-Apoptotic Genes in the Male Germ Cell Line
por: Janecki, Damian M., et al.
Publicado: (2020) -
The FKBP4 Gene, Encoding a Regulator of the Androgen Receptor Signaling Pathway, Is a Novel Candidate Gene for Androgen Insensitivity Syndrome
por: Ilaslan, Erkut, et al.
Publicado: (2020)