Structural assessment of SARS-CoV2 accessory protein ORF7a predicts LFA-1 and Mac-1 binding potential

ORF7a is an accessory protein common to SARS-CoV1 and the recently discovered SARS-CoV2, which is causing the COVID-19 pandemic. The ORF7a protein has a structural homology with ICAM-1 which binds to the T lymphocyte integrin receptor LFA-1. As COVID-19 has a strong immune component as part of the d...

Descripción completa

Detalles Bibliográficos
Autores principales: Nizamudeen, Zubair Ahmed, Xu, Emma-Ruoqi, Karthik, Vivin, Halawa, Mohamed, Arkill, Kenton P., Jackson, Andrew M., Bates, David O., Emsley, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Host-Microbe Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796194/
https://www.ncbi.nlm.nih.gov/pubmed/33305306
http://dx.doi.org/10.1042/BSR20203837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796194/
https://www.ncbi.nlm.nih.gov/pubmed/33305306
http://dx.doi.org/10.1042/BSR20203837

Ejemplares similares