Cargando…

The Role of Hypoxia-Inducible Factor Post-Translational Modifications in Regulating Its Localisation, Stability, and Activity

The hypoxia signalling pathway enables adaptation of cells to decreased oxygen availability. When oxygen becomes limiting, the central transcription factors of the pathway, hypoxia-inducible factors (HIFs), are stabilised and activated to induce the expression of hypoxia-regulated genes, thereby mai...

Descripción completa

Detalles Bibliográficos
Autores principales: Albanese, Adam, Daly, Leonard A., Mennerich, Daniela, Kietzmann, Thomas, Sée, Violaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796330/
https://www.ncbi.nlm.nih.gov/pubmed/33383924
http://dx.doi.org/10.3390/ijms22010268