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Fludarabine, High-Dose Cytarabine and Idarubicin-Based Induction May Overcome the Negative Prognostic Impact of FLT3-ITD in NPM1 Mutated AML, Irrespectively of FLT3-ITD Allelic Burden

SIMPLE SUMMARY: The prognostic relevance of molecular aberrations in acute myeloid leukemia (AML) has been prevalently tested in patients receiving conventional 3+7 induction. Recently, there has been a renewed interest in intensified inductions, but very few data are available on the impact of the...

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Detalles Bibliográficos
Autores principales: Minetto, Paola, Candoni, Anna, Guolo, Fabio, Clavio, Marino, Zannier, Maria Elena, Miglino, Maurizio, Dubbini, Maria Vittoria, Carminati, Enrico, Sicuranza, Anna, Ciofini, Sara, Colombo, Nicoletta, Pugliese, Girolamo, Marcolin, Riccardo, Santoni, Adele, Ballerini, Filippo, Lanino, Luca, Cea, Michele, Gobbi, Marco, Bocchia, Monica, Fanin, Renato, Lemoli, Roberto Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796342/
https://www.ncbi.nlm.nih.gov/pubmed/33374216
http://dx.doi.org/10.3390/cancers13010034