Tuning G-Quadruplex Nanostructures with Lipids. Towards Designing Hybrid Scaffolds for Oligonucleotide Delivery †

Two G-quadruplex forming oligonucleotides [d(TG(4)T)(4) and d(TG(6)T)(4)] were selected as two tetramolecular quadruplex nanostructures because of their demonstrated ability to be modified with hydrophobic molecules. This allowed us to synthesize two series of G-quadruplex conjugates that differed i...

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Detalles Bibliográficos
Autores principales: Grijalvo, Santiago, Clua, Anna, Eres, Marc, Gargallo, Raimundo, Eritja, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796380/
https://www.ncbi.nlm.nih.gov/pubmed/33374392
http://dx.doi.org/10.3390/ijms22010121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796380/
https://www.ncbi.nlm.nih.gov/pubmed/33374392
http://dx.doi.org/10.3390/ijms22010121

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