Spontaneous Mutations in HIV-1 Gag, Protease, RT p66 in the First Replication Cycle and How They Appear: Insights from an In Vitro Assay on Mutation Rates and Types

While drug resistant mutations in HIV-1 are largely credited to its error prone HIV-1 RT, the time point in the infection cycle that these mutations can arise and if they appear spontaneously without selection pressures both remained enigmatic. Many HIV-1 RT mutational in vitro studies utilized repo...

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Detalles Bibliográficos
Autores principales: Yeo, Joshua Yi, Koh, Darius Wen-Shuo, Yap, Ping, Goh, Ghin-Ray, Gan, Samuel Ken-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796399/
https://www.ncbi.nlm.nih.gov/pubmed/33396460
http://dx.doi.org/10.3390/ijms22010370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796399/
https://www.ncbi.nlm.nih.gov/pubmed/33396460
http://dx.doi.org/10.3390/ijms22010370

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