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Novel Epigenetic Eight-Gene Signature Predictive of Poor Prognosis and MSI-Like Phenotype in Human Metastatic Colorectal Carcinomas

SIMPLE SUMMARY: The global methylation profile of two human metastatic colorectal carcinoma subgroups with significantly different outcomes (primary-resistant versus drug-sensitive tumors) was analyzed and compared with the gene expression and methylation data from The Cancer Genome Atlas COlon ADen...

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Detalles Bibliográficos
Autores principales: Condelli, Valentina, Calice, Giovanni, Cassano, Alessandra, Basso, Michele, Rodriquenz, Maria Grazia, Zupa, Angela, Maddalena, Francesca, Crispo, Fabiana, Pietrafesa, Michele, Aieta, Michele, Sgambato, Alessandro, Tortora, Giampaolo, Zoppoli, Pietro, Landriscina, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796477/
https://www.ncbi.nlm.nih.gov/pubmed/33466447
http://dx.doi.org/10.3390/cancers13010158