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More Than Just Simple Interaction between STIM and Orai Proteins: CRAC Channel Function Enabled by a Network of Interactions with Regulatory Proteins

The calcium-release-activated calcium (CRAC) channel, activated by the release of Ca(2+) from the endoplasmic reticulum (ER), is critical for Ca(2+) homeostasis and active signal transduction in a plethora of cell types. Spurred by the long-sought decryption of the molecular nature of the CRAC chann...

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Detalles Bibliográficos
Autores principales: Berlansky, Sascha, Humer, Christina, Sallinger, Matthias, Frischauf, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796502/
https://www.ncbi.nlm.nih.gov/pubmed/33466526
http://dx.doi.org/10.3390/ijms22010471