Prion-Associated Neurodegeneration Causes Both Endoplasmic Reticulum Stress and Proteasome Impairment in a Murine Model of Spontaneous Disease

Prion diseases are a group of neurodegenerative disorders that can be spontaneous, familial or acquired by infection. The conversion of the prion protein PrP(C) to its abnormal and misfolded isoform PrP(Sc) is the main event in the pathogenesis of prion diseases of all origins. In spontaneous prion...

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Detalles Bibliográficos
Autores principales: Otero, Alicia, Betancor, Marina, Eraña, Hasier, Fernández Borges, Natalia, Lucas, José J., Badiola, Juan José, Castilla, Joaquín, Bolea, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796520/
https://www.ncbi.nlm.nih.gov/pubmed/33466523
http://dx.doi.org/10.3390/ijms22010465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796520/
https://www.ncbi.nlm.nih.gov/pubmed/33466523
http://dx.doi.org/10.3390/ijms22010465

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