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Titanium dioxide nanoparticles impair the inner blood-retinal barrier and retinal electrophysiology through rapid ADAM17 activation and claudin-5 degradation

BACKGROUND: Depending on their distinct properties, titanium dioxide nanoparticles (TiO(2)-NPs) are manufactured extensively and widely present in our daily necessities, with growing environmental release and public concerns. In sunscreen formulations, supplementation of TiO(2)-NPs may reach up to 2...

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Detalles Bibliográficos
Autores principales: Chan, Yen-Ju, Liao, Po-Lin, Tsai, Chi-Hao, Cheng, Yu-Wen, Lin, Fan-Li, Ho, Jau-Der, Chen, Ching-Yi, Li, Ching-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796566/
https://www.ncbi.nlm.nih.gov/pubmed/33422125
http://dx.doi.org/10.1186/s12989-020-00395-7