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Deconstructing transcriptional variations and their effects on immunomodulatory function among human mesenchymal stromal cells

BACKGROUND: Mesenchymal stromal cell (MSC)-based therapies are being actively investigated in various inflammatory disorders. However, functional variability among MSCs cultured in vitro will lead to distinct therapeutic efficacies. Until now, the mechanisms behind immunomodulatory functional variab...

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Detalles Bibliográficos
Autores principales: Sun, Changbin, Zhang, Kehua, Yue, Jianhui, Meng, Shufang, Zhang, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796611/
https://www.ncbi.nlm.nih.gov/pubmed/33422149
http://dx.doi.org/10.1186/s13287-020-02121-8