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Synthesis of (R)-mandelic acid and (R)-mandelic acid amide by recombinant E. coli strains expressing a (R)-specific oxynitrilase and an arylacetonitrilase

ABSTRACT: OBJECTIVES: Chiral 2-hydroxycarboxylic acids and 2-hydroxycarboxamides are valuable synthons for the chemical industry. RESULTS: The biocatalytic syntheses of (R)-mandelic acid and (R)-mandelic acid amide by recombinant Escherichia coli clones were studied. Strains were constructed which s...

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Detalles Bibliográficos
Autores principales: Müller, Erik, Sosedov, Olga, Gröning, Janosch Alexander David, Stolz, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796878/
https://www.ncbi.nlm.nih.gov/pubmed/32936375
http://dx.doi.org/10.1007/s10529-020-02998-8